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2016, ISBN: 9788847039094

[ED: Softcover], [PU: Springer / Springer Milan / Springer, Berlin], During the early 19th century, it was discovered that adding yellow (now called white) phosphorous to matchstick heads… Altro …

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Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach - edizione con copertina flessibile

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During the early 19th century, it was discovered that adding yellow (now called white) phosphorous to matchstick heads made it easier to ignite matches. The phosphorous vapors were breath… Altro …

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Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach - edizione con copertina flessibile

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ISBN: 8847039096

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Bisphosphonates and Osteonecrosis of the Jaw: a Multidisciplinary Approach - edizione con copertina flessibile

2016, ISBN: 9788847039094

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Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach - edizione con copertina flessibile

2016, ISBN: 9788847039094

Softcover reprint of the original 1st ed. 2012, Softcover, Buch, [PU: Springer Verlag]

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Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach

During the early 19th century, it was discovered that adding yellow (now called white) phosphorous to matchstick heads made it easier to ignite matches. The phosphorous vapors were breathed in by workers and combined with other chemicals in the body to produce a potent nitrogen-containing bisphosphonate. Today's oral nitrogen-containing bisphosphonates and intravenous nitrogen-containing bisphosphonates circulate around the body the same way as the phosphorous vapors, and are absorbed into bone and ingested by osteoclasts. When this unique binding process of bisphosphonates to bone occurs, osteoclasts are poisoned, and this reduces or eliminates bone turnover. Alveolar bone in the mandible and maxilla turns over more rapidly than in long bones, so the jaws are a better target for bisphosphonate toxicity. It wasn't until 2003 that today's intravenous and oral nitrogen-containing bisphosphonate medications were implicated as major risk factors in the development of exposed necrotic bone of the jaws. Most of the researchers who reported cases of bisphosphonate-induced osteonecrosis of the jaw found that these patients were treated with zoledronate, pamidronate, or a combination of these drugs, which are commonly used for treating breast cancer or myeloma. In about 5% of cases, subjects with BIONJ were being treated for osteoporosis. Precipitating events that contribute to BIONJ are tooth extractions (about 50% of cases), mandibular exostoses, periodontal disease, and local trauma from ill-fitting dentures. It is not known if the placement of dental implants is a precipitating factor. The book aims to meet the need of medical practitioners working in all fields that use bisphosphonates, and to present the conservative and surgical treatment methods currently in use. There will also be detailed information on the literature relating to dental implants in patients treated with bisphosphonates.

Informazioni dettagliate del libro - Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach


EAN (ISBN-13): 9788847039094
ISBN (ISBN-10): 8847039096
Copertina flessibile
Anno di pubblicazione: 2016
Editore: Springer Verlag

Libro nella banca dati dal 2018-04-05T16:41:28+02:00 (Rome)
Pagina di dettaglio ultima modifica in 2022-07-29T15:56:07+02:00 (Rome)
ISBN/EAN: 9788847039094

ISBN - Stili di scrittura alternativi:
88-470-3909-6, 978-88-470-3909-4
Stili di scrittura alternativi e concetti di ricerca simili:
Autore del libro : francesco ponte, save


Dati dell'editore

Autore: Francesco Saverio De Ponte
Titolo: Bisphosphonates and Osteonecrosis of the Jaw: A Multidisciplinary Approach
Editore: Springer; Springer Italia
181 Pagine
Anno di pubblicazione: 2016-08-23
Milano; IT
Stampato / Fatto in
Lingua: Inglese
117,69 € (DE)
120,99 € (AT)
130,00 CHF (CH)
POD
XIII, 181 p.

BC; Hardcover, Softcover / Medizin/Klinische Fächer; Mund-, Kiefer- und Gesichtschirurgie; Verstehen; bisphosphonates; osteonecrosis; pharmacology; surgery; tumor; Oral and Maxillofacial Surgery; Dentistry; Hematology; General Practice and Family Medicine; Pharmacy; Radiology; Zahnheilkunde; Hämatologie; Allgemeinmedizin / Familienmedizin; Pharmazie, Apotheke; Bildgebende Verfahren; BB

Bisphosphonates are commonly prescribed to inhibit bone loss in patients with osteoporosis, as well as osteopenia, cancer, and Paget's disease of the bone. Recently, scientific literature has addressed a possible relationship between bisphosphonates and osteonecrosis of the jaw (ONJ). It is important to note that though the risks for developing ONJ are much higher for cancer patients on intravenous bisphosphonate therapy (used to reduce bone pain), the occurrence of ONJ also in patients treated with oral BF for osteoporosis has been also highlighted, though rarely. On the basis of the large use of BF, of their pharmacokinetics, of the systemic and local risk factors, physicians prescribing them and dental surgeons should be well informed on the various aspects of the problem. Aim of this volume is to offer an update on the current status of prevention, and on the current conservative and surgical treatments. The multidisciplinary approach will be very much appreciated by GP’s, the different specialists using bisphosphonates and by dental surgeons.
First multidisciplinary text on the subject, by worldwide experts Update of the latest advances, technical details, and expert advice regarding this subject Presents multiple designs, explanatory figures on physiopathogenesis, and clinical imaging Clinical case discussions and practical advice for incorporation into common practice

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